Sunday, March 10, 2013

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Physical exercise is any bodily activity that enhances or maintains physical fitness and overall health and wellness. It is performed for various reasons including strengthening muscles and the cardiovascular system, honing athletic skills, weight loss or maintenance, as well as for the purpose of enjoyment. Frequent and regular physical exercise boosts the immune system, and helps prevent the ?diseases of affluence? such as heart disease, cardiovascular disease, Type 2 diabetes and obesity.It also improves mental health, helps prevent depression, helps to promote or maintain positive self-esteem, and can even augment an individual?s sex appeal or body image, which is also found to be linked with higher levels of self-esteem.Childhood obesity is a growing global concern and physical exercise may help decrease some of the effects of childhood and adult obesity. Health care providers often call exercise the ?miracle? or ?wonder? drug?alluding to the wide variety of proven benefits that it provides.

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Source: http://stek.org/videos/seth-feroce-muscles-posing-bodybuilders/

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Most Beautiful Items: March 2-8, 2013

Stop here, right here. There are so many wonderful things below for you to look at. From teeny tiny houses to crazy structures made from ice, there's plenty for you to feast your eyes on before you get your weekend started. More »


Source: http://feeds.gawker.com/~r/gizmodo/full/~3/EJ998P6xhrA/most-beautiful-items-march-2+8-2013

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Yahoo's CEO gets $1.1M bonus after 5 months at helm

Yahoo CEO Marissa Mayer received a $1.1 million bonus for her first five-and-half months running the Internet company, during which time the company's stock gained 46 percent.

The award disclosed Wednesday in documents filed with the Securities and Exchange Commission supplements Mayer's annual salary of $1 million and $56 million in long-term stock compensations that she received after Yahoo Inc. lured her away from Google Inc. to become its CEO last July. The amount included $14 million in stock to offset the loss of money that she would have received had she remained at Google.

The 37-year-old Mayer is eligible for an annual bonus of up to $2 million. Yahoo adjusted last year's bonus to reflect that Mayer spent less than half the year as CEO.

Related story: Is telecommuting dead? Don't count on it, experts say

To put this into perspective, the highest-paid CEO in America last year, according to CNBC, was Honeywell International's David Cote, who received average compensation of $25 million. Cote has been with Honeywell since 2002.

Earlier this week, Ford Motor Co awarded CEO Alan Mulally performance bonuses worth almost $12 million. Mulally has been at the helm of Ford since 2006 and has led the company's turnaround.

The Associated Press contributed to this report.

Source: http://www.nbcnews.com/business/yahoos-marissa-mayer-gets-1-1m-bonus-after-5-months-1C8775298

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New player in electron field emitter technology makes for better imaging and communications

Mar. 8, 2013 ? Scientists at the National Institute of Standards and Technology (NIST) and the University of Maryland, College Park, have built a practical, high-efficiency nanostructured electron source. Described in the journal Nanotechnology, this new, patent-pending technology could lead to improved microwave communications and radar, and more notably to new and improved X-ray imaging systems for security and health-care applications.

While thermionic electron sources such as the hot filaments inside cathode ray tubes have largely been replaced by LEDs and liquid crystals for display screens and televisions, they are still used to produce microwaves for radar and X-rays for medical imaging. Thermionic sources use an electric current to boil electrons off the surface of a wire filament, similar to the way an incandescent light bulb uses an electric current to heat a wire filament until it glows.

And like an incandescent light bulb, thermionic sources are generally not very energy efficient. It takes a lot of power to boil off the electrons, which spew in every direction. Those that aren't lost have to be captured and focused using a complicated system of electric and magnetic fields. Field emission electron sources require much less power and produce a much more directional and easily controllable stream of electrons.

To build their field emission source, the NIST team took a tough material -- silicon carbide -- and used a room-temperature chemical process to make it highly porous like a sponge. They then patterned it into microscopic emitting structures in the shape of pointed rods or sharp-edged fins. When an electric field is applied, these novel field emitters can produce an electron flow comparable to a thermionic source but without all the disadvantages -- and with many advantages.

According to co-inventor Fred Sharifi, the new field emitters have inherently fast response times compared with thermionic sources, and the absence of heat makes it easier to create arrays of sources. Moreover, the porous nanostructure of the emitters makes them very reliable. Even if the emitter surface wears away during use -- a common problem -- the newly exposed material continues to work just as well.

Sharifi says that the NIST field emitters hold the potential to enhance the resolution and quality of X-ray images and allow for new modes of detection.

"X-ray images are based on the density of the material being examined, which limits their ability to see certain types of materials, including some types of explosives," says Sharifi. "Our field emitter will let us see not just that something is there, but, because we can build large arrays and place them at different angles, we can identify the material in question by looking at how the X-rays coming from different directions scatter from the object."

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Story Source:

The above story is reprinted from materials provided by National Institute of Standards and Technology (NIST).

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Myung-Gyu Kang, Henri J Lezec, Fred Sharifi. Stable field emission from nanoporous silicon carbide. Nanotechnology, 2013; 24 (6): 065201 DOI: 10.1088/0957-4484/24/6/065201

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/matter_energy/electricity/~3/vLzws7REja0/130308143850.htm

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Skull cracked? Print a new one

A patient with a damaged skull has undergone a radical new treatment: having 75 percent of his damaged skull replaced with a 3-D printed prosthetic. It's the first time such a skull replacement has been used.

The recipient of the historic skull plate is being kept anonymous, but was one of the hundreds of people each month in the U.S. alone who suffer serious damage to their skull ? serious, that is, but not irreparable.

For smaller plates, a piece of premade metal or plastic will serve, but for replacing larger portions of the skull (needless to say, the patient's 75 percent is at the high end), something more custom needed to be devised. Oxford Performance Materials specializes in this.

By scanning the skull of the patient and printing a custom skull using a proprietary body-friendly polymer, the company's team can create a prosthetic within two weeks that is perfectly fitted to the contours of the patient's brain and bone.

The process was only just approved by the Food and Drug Administration on Feb. 18, and the first operation took place this week.

No pictures of the actual patient with his new skull were made available, both to preserve his privacy and because such a photo would likely be quite gruesome such a short time after major surgery. The photo above, however, does show how the material would look before implanting.

Now that OsteoFab prosthetics, as they are called, are approved, OPM hopes to expand into other areas ? of both the world and the body. "We see no part of the orthopedic industry being untouched by this," OPM's president, Scott De Felice, told TechNewsDaily.

Devin Coldewey is a contributing writer for NBC News Digital. His personal website is coldewey.cc.

Source: http://www.nbcnews.com/technology/futureoftech/skull-cracked-print-new-one-1C8780228

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Saturday, March 9, 2013

New drug shows promise in fighting inflammatory breast cancer

Mar. 7, 2013 ? Researchers in the University of Delaware's Department of Biological Sciences are investigating a new drug that has shown positive results in early tests of its ability to fight a rare and aggressive form of breast cancer.

A small, pilot study of the drug found that inflammatory breast cancer (IBC) tumors in mice -- which grew to four times their original size in a 10-day period if untreated -- remained stable in size when treated with the drug. When a small amount of a traditional chemotherapy drug, which has limited effectiveness in IBC, was combined with the new drug, the number of tumor cells was cut in half.

"It's a nontoxic drug, it's inexpensive, and it's easy to administer," said Kenneth L. van Golen, associate professor of biological sciences and a senior research scientist with the Helen F. Graham Cancer Center at Christiana Care. "To me, it looks like a home run."

Van Golen specializes in IBC research, and the new drug was first brought to his attention by doctoral student Madhura Joglekar. She had read about a small pharmaceutical company in Texas that had developed it to treat gastrointestinal cancer. But she realized that it was designed to target those tumors in the same kind of way that might be effective with IBC tumors. Specifically, the novel drug targets the platelet-derived growth factor receptor.

IBC is relatively rare, uses a different pathway in which it spreads, or metastasizes, and is much more deadly than the common form of breast cancer. Receptors in the typical form of the disease are on the outside of the cell, but in IBC they are on the inside, making them harder to target for treatment.

"This new drug targets receptor molecules and we already knew that's a good approach for IBC," Joglekar said. She brought the studies to van Golen, who contacted manufacturer Arog Pharmaceuticals, and was given the go-ahead to work with the drug, which already is in clinical trials with gastrointestinal cancer patients.

In Joglekar's studies with mice, she and van Golen were especially encouraged by the way the drug seems to significantly increase the effectiveness of the usual chemotherapy. This compound effect, van Golen said, might mean that IBC patients could undergo less extensive chemotherapy, with resulting fewer side effects, than they do now.

Because IBC is highly aggressive, current treatments of surgery, chemotherapy and radiation are generally intensive and harsh. The disease is systemic, spreading rapidly through the lymphatic system, and is often misdiagnosed at first because it resembles an infection more than a traditional form of breast cancer.

That's another reason to be optimistic about the new drug, van Golen said: Because it appears to be so nontoxic, it could be given to a patient, along with an antibiotic, even before the diagnosis is certain, with no harm done if the condition turns out to be merely an infection. But if IBC were later diagnosed, the crucial early cancer treatment would have started without delay.

Joglekar presented the results of the research at an international IBC conference in December, where it received a great deal of positive notice, van Golen said. If preclinical studies continue to produce promising results, he estimated that the drug could be used in Phase 3 clinical trials (the final phase before a drug is usually approved for general use) in two to three years.

Meanwhile, Joglekar said she hopes to conduct longer-term studies on the drug's effects on IBC tumors and on the way it seems to sensitize cells in those tumors to chemotherapy, making that treatment more effective, and also to explore exactly how the drug works at the molecular level.

In addition to investigating its interaction with chemotherapy drugs, van Golen plans to study whether it could also augment the effects of radiation treatment.

"I think this drug is a real winner," he said. "We just need to learn more about how to use it."

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The above story is reprinted from materials provided by University of Delaware, via Newswise.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/iL15MTRNtWU/130307175511.htm

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Thursday, March 7, 2013

U.N. says Golan peacekeepers detained by Syrian rebels

UNITED NATIONS (Reuters) - The United Nations said about 20 peacekeepers were detained in Syria near the Israeli-occupied Golan Heights on Wednesday by around 30 fighters linked to Syrian armed opposition groups

The United Nations said it has sent a team to resolve the situation, while the 15-member Security Council condemned the incident and demanded the immediate release of the peacekeepers.

U.N. peacekeeping chief Herve Ladsous told the council in an emergency briefing that the fighters who had detained the peacekeepers were "associated with Syrian armed opposition group elements," said Russian U.N. Ambassador Vitaly Churkin, who is president of the council in March.

He added that the captors have made "some demands associated with the actual situation on the ground in Syria." He gave no further detail.

Videos purporting to show Syrian rebels with the seized convoy were posted to YouTube on Wednesday. Syria's two-year civil war, which has killed more than 70,000 people, has been spilling into the Golan Heights area.

"The U.N. observers were on a regular supply mission and were stopped near Observation Post 58, which had sustained damage and was evacuated this past weekend following heavy combat in close proximity, at Al Jamlah," the United Nations said in a statement issued in New York.

Israel captured the Golan Heights from Syria in a 1967 war. Syrian troops are not allowed in the area of separation under a 1973 ceasefire formalized in 1974. Israel and Syria are still technically at war. The area is patrolled by U.N. peacekeepers.

Israel warned the U.N. Security Council on Monday that it could not be expected to "stand idle" as Syria's civil war spills over its border, while Russia's Churkin accused armed groups of undermining security between the states by fighting in the Golan Heights.

(Reporting by Michelle Nichols and Louis Charbonneau; Editing by Doina Chiacu)

Source: http://news.yahoo.com/u-n-says-golan-peacekeepers-detained-syrian-rebels-191046956.html

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